Proposed Data Collections Submitted for Public Comment and Recommendations

DEPARTMENT OF HEALTH AND HUMAN SERVICES

Centers for Disease Control and Prevention

[INFO-99-43]

Proposed Data Collections Submitted for Public Comment and

Recommendations

In compliance with the requirement of Section 3506 (c) (2) (A) of

the Paperwork reduction Act of 1995, the Center for Disease Control and

Prevention is providing opportunity for public comment on proposed data

collection projects. To request more information on the proposed

projects or to obtain a copy of the data collection plans and

instruments, call the CDC Reports Clearance Officer on (404) 639-7090.

Comments are invited on: (a) Whether the proposed collection of

information is necessary for the proper performance of the functions of

the agency, including whether the information shall have practical

utility; (b) The accuracy of the agency's estimate of the burden of the

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proposed collection of information; (c) Ways to enhance the quality,

utility, and clarity of the information to be collected; and (d) Ways

to minimize the burden of the collection of information on respondents,

including through the use of automated collection techniques for other

forms of information technology. Send comments to Seleda Perryman, CDC

Assistant Reports Clearance Officer, 1600 Clifton Road, MS-D24,

Atlanta, GA 30333. Written comments should be received within 60 days

of this notice.

Proposed Projects

Multi-Center Cohort Study to Assess the Risk and Consequences of

Hepatitis C Virus Transmission from Mother to Infant (0920-0344)--

Renewal--The National Center for Infectious Diseases (NCID)--The

purpose of the proposed study is (1) To determine the incidence of

vertical hepatitis C virus (HCV) transmission, (2) To assess risk

factors for vertical HCV transmission, (3) To assess the clinical

course of disease among infants with HCV infection, and (4) To assess

diagnostic methods for detecting HCV infection in infants. HCV is a

blood-borne pathogen and is the major etiologic agent of what was

previously referred to as parenterally-transmitted non-A, non-B

hepatitis. Diagnostic tests for HCV infection have recently been

developed and HCV has been demonstrated to account for about 20% of all

cases of viral hepatitis in the United States. Virtually all adults

with acute HCV infection may become chronically infected and 50%-60%

may develop chronic liver disease with persistently elevated liver

enzymes. Of adults with chronic liver disease, 30%-60% may develop

chronic active hepatitis and 5%-20% may develop cirrhosis within five

years after illness onset. HCV is also a major contributing cause of

hepatocellular carcinoma. An estimated 8,000-10,000 chronic liver

disease deaths per year in the United States are attributable to HCV

infection. There are no costs to respondents other than their time to

participate.

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Burden hours

Form name No. of No. responses per Total burden

respondents per respondent respondent hours

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Form A.......................................... 300 1 0.25 75

Form B.......................................... 1200 1 0.25 300

Form C.......................................... 300 1 0.10 30

Form E.......................................... 300 1 0.25 75

Form G.......................................... 300 8 0.10 240

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Total....................................... .............. .............. .............. 720

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2. Chronic Fatigue Syndrome (CFS) Surveillance and Related Studies,

Prevalence and Incidence of Fatiguing Illness in Sedgewick County,

Kansas (0920-0401)--Renewal--The National Center for Infectious

Diseases (NCID)--A Population-Based CFS Study was done previously in

Kansas in 1997. Data from this cross-sectional, random-digit-dial

survey of prolonged fatiguing illness in Wichita, Kansas will be added

to the data previously obtained during the past 24-months from this

population.

The proposed study continues the Sedgwick County study using

identical methodology and data collection instruments. Beginning with a

random-digit-dial telephone survey to identify previously identified

fatigued and non-fatigued individuals, followed by a detailed telephone

interview to obtain additional data on participants' health status

during the last 12-month period. Study objectives remain to refine

estimates of CFS in Wichita, identify similarities and differences

among fatigued and non-fatigued subjects and to describe the clinical

course of fatiguing illness in this population.

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No. of Average burden/

Respondents No. of responses/ respondent Total burden

respondents respondent (in hrs.) (in hrs.)

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Individuals screened............................ 4,500 1 0.083 374

Individuals interviewed......................... 4,500 1 0.25 1,125

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Total....................................... .............. .............. .............. 1,499

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Nancy Cheal,

Acting Associate Director for Policy, Planning, and Evaluation, Centers

for Disease Control and Prevention (CDC).

[FR Doc. 99-25683 Filed 10-1-99; 8:45 am]

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