Opinion

Alfacell Corp. v. Anticancer, Inc.

Court
Trademark Trial and Appeal Board
Filed
Jun 22, 2004
Status
Published
Author
Quinn
On the bench
Sams, Seeherman, Quinn
Cited by
0 cases
Authority
More cited than 39.5%

The opinion

THIS DECISION IS CITABLE

AS PRECEDENT OF THE

TTAB

Hearing:

March 4, 2004 Mailed: 6/22/2004

UNITED STATES PATENT AND TRADEMARK OFFICE

_____

Trademark Trial and Appeal Board

_____

Alfacell Corporation

v.

Anticancer, Inc.

_____

Cancellation No. 92032202

_____

Mark H. Jay for Alfacell Corporation.

Jennifer Lee Taylor of Morrison & Foerster for Anticancer,

Inc.

_____

Before Sams, Seeherman and Quinn, Administrative Trademark

Judges.

Opinion by Quinn, Administrative Trademark Judge:

Alfacell Corporation has petitioned to cancel a

registration owned by Anticancer, Inc. of the mark ONCASE

for “therapeutic compositions containing reagents for in

vivo anticancer use.”1 As grounds for cancellation under

Section 2(d) of the Trademark Act, petitioner alleges that

respondent’s mark, when used in connection with respondent’s

goods, so resembles petitioner’s previously used and

1

Registration No. 1,987,445, issued July 16, 1996; Section 8

affidavit filed and accepted.

Cancellation No. 92032202

registered mark ONCONASE for “pharmaceuticals, namely,

cancer-treating drugs,”2 as to be likely to cause confusion.

Respondent, in its answer, has denied the salient

allegations of likelihood of confusion. Respondent also has

set forth allegations labeled as “Affirmative Defenses,”

including that the petition is barred by laches.

The record consists of the pleadings; the file of the

involved registration; trial testimony, with related

exhibits, taken by each party; and excerpts from printed

publications and printouts of pages of various websites

retrieved from the Internet,3 all introduced by way of

respondent’s notices of reliance. The parties filed briefs,

and both were represented by counsel at an oral hearing held

before the Board.

The Parties

Both parties are involved in the development of cancer-

treating drugs. Petitioner’s drugs include one that is

delivered intravenously to a patient to treat mesothelioma,

a cancer caused by exposure to asbestos. According to the

2

Registration No. 1,651,885, issued July 23, 1991; renewed.

3

Internet evidence is not proper subject matter for introduction

by notice of reliance because the evidence is not self-

authenticating. As the Board has stated in the past, the element

of self-authentication cannot be presumed to be capable of being

satisfied by information obtained and printed out from the

Internet. Raccioppi v. Apogee Inc., 47 USPQ2d 1368, 1370 (TTAB

1998). See also TBMP §704.08 (2d ed. rev. 1, March 2004).

Because the parties have treated this evidence as if properly

made of record, however, we will deem it to be in the record by

stipulation of the parties.

2

Cancellation No. 92032202

testimony of Kuslima Shogen, petitioner’s founder and chief

executive officer, this drug, marketed under the mark

ONCONASE, is petitioner’s “flagship” product. The drug is

an enzyme derived from the Rana pipiens frog. Petitioner’s

product is in clinical trials being conducted at 33 clinical

sites.

Respondent’s product marketed under the mark ONCASE is

a protein which degrades methionine for treatment of human

cancers. Robert Hoffman, respondent’s president and chief

executive officer, testified that the ONCASE brand drug is

currently in pre-clinical trials in the United States, and

in clinical trials outside of this country. Respondent’s

product is administered intravenously in conjunction with

chemotherapy; this product, according to Dr. Hoffman’s

testimony, improves the efficacy of the chemotherapy used in

treating a variety of cancers.

As shown by the record, clinical trials of

pharmaceuticals, that is, trials in human beings, commence

only after an applicant’s Investigational New Drug

Application (“IND”) has been approved by the Food and Drug

Administration (“FDA”). Before even beginning the FDA

approval process, all drugs must undergo extensive pre-

clinical testing. After the pre-clinical testing is

complete, the developer of the drug files an IND seeking

approval for testing on humans. If the IND is approved, the

3

Cancellation No. 92032202

drug is tested on humans in three phases of clinical trials.

The phases may last for several years. It is only after

successful completion of all three phases of clinical trials

that the developer of the drug can file a New Drug

Application (“NDA”) with the FDA seeking approval of the new

drug for sales to the public. According to the record in

the present case, neither party has filed an NDA for its

respective drug herein.

ISSUES

There is no dispute regarding petitioner’s priority of

use of its mark ONCONASE in connection with its cancer

treatment drug. The parties’ respective testimony

establishes that petitioner’s first use of its mark ONCONASE

occurred in January, 1991, whereas respondent first used its

mark ONCASE in October 1995. Therefore, the only remaining

issues in this case are likelihood of confusion and laches.

Before turning to the merits of those issues, however, our

attention is directed to other subsidiary matters raised by

the parties.

The parties filed, earlier in this proceeding, cross

motions for partial summary judgment on the pleaded issue of

abandonment. The parties were at odds over whether

respondent’s activities under its mark constituted “use in

commerce” as contemplated under the Trademark Act. The

Board characterized the issue as follows: Whether, as a

4

Cancellation No. 92032202

matter of law, respondent’s shipments of its pharmaceutical

products for purposes of pre-clinical trials within the

United States, and for purposes of clinical trials in

foreign countries constitute “use in commerce.” In an order

dated September 24, 2002, the Board ruled in respondent’s

favor, entering partial summary judgment on the issue of

abandonment. The Board found that Congress intended the

term “use in commerce” to encompass shipments of

pharmaceuticals for pre-clinical trials in this country and

for clinical trials abroad prior to receiving FDA approval

as a reflection of common industry practice; that the “use

in commerce” Congress can regulate is the actual shipment of

the pharmaceuticals overseas; and that it is not necessary

that Congress be able to regulate the clinical testing. In

that interlocutory order, the Board indicated that “this

case will proceed solely on the issues of likelihood of

confusion and priority of use.”

In its brief on the case, petitioner raises for the

first time a claim that respondent’s use of its mark was

unlawful. Petitioner makes reference to this unpleaded

“subsidiary” issue as follows: “Whether the Board should

draw an adverse inference against [respondent] for the

improper refusal of its President to answer questions posed

during his trial testimony, and to consequently hold the

ONCASE registration invalid as having been improperly issued

5

Cancellation No. 92032202

on the basis of unlawful commerce.” (Brief, p. 5).

Petitioner contends that respondent “stonewalled highly

relevant cross-examination during its trial testimony and

the Board should draw a dispositive adverse inference

against it.” (Brief, p. 19).

In connection with its motion for summary judgment,

respondent submitted the declaration of Dr. Hoffman wherein

he indicated that respondent’s pharmaceutical marketed under

the mark ONCASE was shipped in commerce to Mexico for

clinical trials. The declaration was introduced later at

trial as an exhibit during Dr. Hoffman’s testimony

deposition. Petitioner now claims that respondent’s use was

unlawful because the FDA had not authorized shipment of

respondent’s drug for use in clinical trials. Petitioner

contends that it was entitled to cross examine Dr. Hoffman

about the legality of that alleged unauthorized exportation.

In view of Mr. Hoffman’s refusal to answer questions

regarding these shipments, petitioner urges that “the Board

should infer that the exportation of ONCASE from the United

States to Mexico preceded, and therefore took place in the

absence of, any authorization by the FDA to use the drug in

a clinical trial.” Petitioner concludes that the adverse

inference to be drawn from Dr. Hoffman’s refusal to answer

questions on these shipments is that respondent committed a

6

Cancellation No. 92032202

per se violation of 21 CFR §312.110.4 Petitioner asserts

that an IND has never been issued for the ONCASE brand drug,

and that respondent’s exportation of the drug for clinical

trials in Mexico occurred before the FDA had authorized

respondent to export the drug.

Respondent has objected to consideration of this issue,

maintaining that the issue was not added by petitioner in

any amended pleading, and that there has been no trial of

this issue. Respondent goes on to assert that, in any

event, the only evidence on this issue is the relevant

regulation itself, and that this evidence standing alone

falls far short of establishing that respondent’s use was

unlawful.

We find that petitioner’s claim of unlawful use is

untimely and, thus, we decline to consider it. Petitioner

knew of this possible claim for relief at least as early as

when respondent filed its motion for summary judgment which

was supported by the same affidavit of Dr. Hoffman upon

which petitioner now relies as a basis for its newly raised

claim. Yet petitioner did not raise this claim until its

brief on the case. Hilson Research Inc. v. Society for

4

The regulation provides, in relevant part, that an

investigational new drug intended for export from the United

States must comply with FDA regulations if an IND is in effect

for the drug, or if an IND is not in effect, then the FDA must

authorize shipment of the drug for use in any clinical

investigation.

7

Cancellation No. 92032202

Human Resource Management, 27 USPQ2d 1423, 1439-40 (TTAB

1993); and Chicago Corp. v. North American Chicago Corp., 20

USPQ2d 1715, 1717 n. 5 (TTAB 1991). Petitioner simply

failed to promptly amend the petition for cancellation after

it learned of facts which, petitioner contends, establish

this additional claim. To allow petitioner to raise the

claim at this late juncture would be an unfair surprise to

respondent.

Further, given respondent’s clear and repeated

objections to the questions relating to the purported

unlawful use, there was neither an implied nor an explicit

trial of this issue. Fed. R. Civ. P. 15(b). The objections

were well taken inasmuch as the issue of unlawful use was

not pleaded and the Board, in its decision on the motion for

summary judgment, had explicitly stated that the only issues

for trial were priority and likelihood of confusion.

Therefore, the questions being posed went beyond the scope

of the issues in this case. Given that respondent’s

objections were well taken, we have not drawn an adverse

inference from Dr. Hoffman’s refusal to answer the questions

pertaining to respondent’s exportation of its drug to

Mexico. TBMP §707.03(d) (2d ed. rev. 1, March 2004). Cf.:

Levi Strauss & Co. v. R. Josephs Sportswear Inc., 28 USPQ2d

1464, 1467 (TTAB 1993).

8

Cancellation No. 92032202

Accordingly, we have given no consideration on the

merits to petitioner’s claim that respondent’s use was

unlawful.

LIKELIHOOD OF CONFUSION

Our determination under Section 2(d) is based on an

analysis of all of the facts in evidence that are relevant

to the factors bearing on the likelihood of confusion issue.

In re E. I. du Pont de Nemours & Co., 476 F.2d 1357, 177

USPQ 563 (CCPA 1973).

In any likelihood of confusion analysis, two key

considerations are the similarities or dissimilarities

between the marks and the similarities or dissimilarities

between the goods. Federated Foods, Inc. v. Fort Howard

Paper Co., 544 F.2d 1098, 192 USPQ 24 (CCPA 1976). These,

and other du Pont factors deemed pertinent in the proceeding

now before us, are discussed below.

THE PARTIES’ GOODS

Petitioner’s goods, in its pleaded registration, are

identified as “pharmaceuticals, namely, cancer-treating

drugs” while respondent’s goods, in the registration sought

to be cancelled, are identified as “therapeutic compositions

containing reagents for in vivo anti-cancer use.” As often

stated, Board proceedings are concerned with registrability

and not use of a mark and, thus, the identification of goods

in the respective registrations herein frames the issue.

9

Cancellation No. 92032202

Cunningham v. Laser Golf Corp., 222 F.3d 943, 55 USPQ2d 1842

(Fed. Cir. 2000); and Canadian Imperial Bank of Commerce v.

Wells Fargo Bank, N.A., 811 F.2d 1490, 1 USPQ2d 1813 (Fed.

Cir. 1987). Both products here are pharmaceuticals used in

treating cancer patients. As identified in the respective

registrations, we find that the goods are legally identical

for purposes of our likelihood of confusion determination.

Respondent contends that the goods “look dramatically

different from one another and are used in distinct

treatment regimes.” More specifically, respondent states

that because both products are administered intravenously,

the medical professionals administering the products will

see that “[a] bag of clear liquid [petitioner’s product] is

highly distinguishable from a bag of brilliant yellow liquid

[respondent’s product].” (Brief, p. 18). Simply put, these

distinctions are of little moment in our likelihood of

confusion analysis which, to reiterate, is based on a

comparison of the goods as identified in the involved

registrations. Moreover, the question is whether the

relevant classes of purchasers are likely to confuse the

source of the goods, not the goods themselves.

THE PARTIES’S MARKS

Insofar as the marks are concerned, we initially note

that when marks are applied to legally identical goods, as

is the case here, “the degree of similarity [between the

10

Cancellation No. 92032202

marks] necessary to support a conclusion of likely confusion

declines.” Century 21 Real Estate Corp. v. Century Life of

America, 970 F.2d 874, 23 USPQ2d 1698, 1700 (Fed. Cir.

1992).

The marks are similar in sound and appearance. Both

marks begin with ONC and end in ASE (the scientific names of

petitioner’s and respondent’s drugs are, respectively,

“ranpirnase” and “recombinant methioninase”). Although

petitioner’s mark includes an additional syllable, it is the

middle portion of the mark. As seen and spoken, this middle

portion may be missed by many of the relevant purchasers.

As to meaning, we find that the first portion of the

respective marks, “ONC-”, connotes that each product has

something to do with oncology. Thus, while each mark is

suggestive, the marks convey, at least superficially, the

same basic idea. Notwithstanding this suggestiveness, Dr.

Costanzi, a board certified physician in medical oncology,

testified that he was not aware of any other “ONC-” marks in

the field. The record is otherwise devoid of any probative

evidence showing third-party uses or registrations of

similar marks in the oncology field.

In sum, we find that the similarities between the marks

outweigh the differences.

11

Cancellation No. 92032202

TRADE CHANNELS

There are certain other duPont factors that are

relevant in the present case. The first relates to channels

of trade.

Respondent concedes that the goods presently move in

overlapping channels of trade, but goes on to assert that

these channels consist of tightly controlled pre-clinical

and clinical trials. Respondent contends that clinical

trials are designed so that confusion cannot occur;

according to respondent, confusion is all but impossible due

to careful labeling and security procedures that are

followed to ensure the accuracy of the test results.

Respondent’s argument to restrict the trade channels

factor to these trials, and to not consider the general

pharmaceutical market, is misplaced. Neither of the

identifications of goods includes a restriction to pre-

clinical or clinical trials. We must assume, therefore,

that the respective drugs will both gain FDA approval and

subsequently travel in the future in the same general

pharmaceutical trade channels.5

5

Respondent also contends that petitioner’s product is unlikely

to pass the clinical stage and, accordingly, the drug will never

make its way to the pharmaceutical market for sale. Suffice it

to say that the likelihood that the FDA will or will not approve

petitioner’s drug for market use, or that the efficacy of

respondent’s drug is greater than that of petitioner’s drug, is

entirely irrelevant to the issue of likelihood of confusion

before us.

12

Cancellation No. 92032202

Inasmuch as the identifications of goods do not include

any limitations, it is assumed that the goods move through

the same trade channels, namely all trade channels normal

for goods of this type in the healthcare field. These would

in the future include hospitals and other healthcare

facilities. However, the goods, as identified, are not

limited to hospital use, and it is reasonable to assume

that, at some point in the future, the drugs may be

dispensed outside of the hospital setting, perhaps even as

medications which can be taken by the patient at home. Dr.

Costanzi touched on this point when he testified about the

coming days of “brown bag” pharmaceuticals. (Dep., pp. 14-

16). Thus, the precautionary controls over cancer-treating

drugs that generally exist within the hospital may be lost

when prescriptions for such drugs might be filled at the

local drug store or pharmacy.

CONDITIONS OF SALE

In considering the conditions of sale of the respective

products, we note that the drugs would be prescribed by

physicians, dispensed by pharmacists and normally

administered by healthcare professionals such as doctors and

nurses. We acknowledge that such persons are sophisticated

and are not prone to carelessness. Nonetheless, we find

that confusion is likely, even among these healthcare

professionals, where these similar goods are marketed under

13

Cancellation No. 92032202

the similar marks involved herein; there is no reason to

believe that medical expertise as to pharmaceuticals will

ensure that there will be no likelihood of confusion as to

source or affiliation. See: In re Merck & Co., Inc., 189

USPQ 355 (TTAB 1975). See also: KOS Pharmaceuticals Inc.

v. Andrx Corp., ___F.3d___ (3d Cir., No. 03-3977, May 24,

2004). As Dr. John Costanzi testified, contrary to the gist

of Dr. Hoffman’s remarks on this point, mistakes have been

made where cancer patients were given the wrong drug, as a

result of name or trademark confusion, with dire

consequences (pointing to a reported death due to confusion

between Taxol and Taxotere). (Dep. pp. 13-19; and exhibit

no. 16 which is an article captioned “Lethal Confusion”

retrieved from Forbes.com). See generally: J.T. McCarthy,

McCarthy on Trademarks and Unfair Competition, §19:149 (4th

ed. 2004).

Moreover, as noted above, the parties’ drugs, as

identified, also could be dispensed outside of the hospital

setting, such that the ultimate users will have direct

contact with them. As stated in KOS Pharmaceuticals Inc.,

id., citing Checkpoint Sys., Inc. v. Check Point Software

Techs., Inc., 269 F.3d 270, 285 (3d Cir. 2001), “[w]here

both professionals and the general public are relevant

consumers, ‘the standard of care to be exercised....will be

equal to that of the least sophisticated consumer in the

14

Cancellation No. 92032202

class.’” Thus, we must be sensitive to the fact that

patients from the general public will not exercise the

degree of care exhibited by medical professionals. As also

stated by the Third Circuit in KOS Pharmaceuticals Inc.,

id.: “While doctors and pharmacists play a gate-keeping

role between patients and prescription drugs, they are not

the ultimate consumers. Patients are. Courts have noted

that drugs are increasingly marketed directly to potential

patients through, for example, ‘ask-your-doctor-about-Brand-

X’ style advertising.” [citations omitted].

ACTUAL CONFUSION

The absence of evidence of actual confusion does not

compel a different result. The tight controls over drugs

during clinical testing may have prevented any meaningful

opportunity for confusion to occur between the marks.

Further, respondent has shipped only seven vials of the drug

in connection with pre-clinical testing in this country, and

it would appear that any opportunity for confusion has been

virtually nonexistent. Cunningham v. Laser Golf Corp.,

supra at 1847 [In order for lack of actual confusion to be a

meaningful factor, there must be evidence showing that there

has been an opportunity for incidents of actual confusion to

occur.] In any event, the test here is likelihood of

confusion, and actual confusion need not be found in order

to conclude that there is a likelihood of confusion between

15

Cancellation No. 92032202

the marks. Weiss Associates Inc. v. HRL Associates Inc.,

902 F.2d 1546, 14 USPQ2d 1840 (Fed. Cir. 1990).

CONCLUSION

We conclude, based on a preponderance of the evidence,

that there is a likelihood of confusion when the marks

ONCONASE and ONCASE are contemporaneously used on the

parties’ respective cancer-treating drugs.

As a final point, prior decisions state that, where the

marks are used on pharmaceuticals and confusion as to source

can lead to serious consequences, it is extremely important

to avoid that which will cause confusion. This further

supports our conclusion herein. See: Glenwood

Laboratories, Inc. v. American Home Products Corp., 455 F.2d

1384, 173 USPQ 19 (CCPA 1972); Blansett Pharmacal Co. Inc.

v. Carmrick Laboratories Inc., 25 USPQ2d 1473 (TTAB 1992);

Schering Corp. v. Alza Corp., 207 USPQ 504 (TTAB 1980); and

American Home Products Corp. v. USV Pharmaceutical Corp.,

190 USPQ 357 (TTAB 1976). See also: KOS Pharmaceuticals

Inc. v. Andrx Corp., supra. See generally: McCarthy on

Trademarks and Unfair Competition, supra, §23:32.

LACHES

The last issue for us to consider is respondent’s

affirmative defense of laches. Respondent contends that

petitioner’s undue and unreasonable delay in asserting its

rights requires dismissal of the petition for cancellation.

16

Cancellation No. 92032202

In the present case, respondent specifically asserts that

petitioner knew or should have known that it had a cause of

action as early as July 5, 1994, when respondent’s mark

ONCASE was published for opposition; that the resulting

registration of the mark in 1996 put petitioner on

constructive notice of respondent’s ownership and use of the

mark; and that rather than taking timely action, petitioner

waited until three days prior to the fifth anniversary date

of the registration to file the present petition for

cancellation. Respondent contends that it has been

prejudiced by petitioner’s delay in that it has built up and

promoted its mark ONCASE in reliance on its registration

thereof and petitioner’s silence. Respondent maintains that

its product has been extensively promoted through trade

shows, conferences and presentations, and that if

respondent’s registration is cancelled, it will lose the

value of its extensive investment through its promotion of

the mark.

Petitioner responds by characterizing the defense as

“makeweight” and asserting that respondent’s investment in

the mark ONCASE has been only minimal.

Respondent, as the party raising the affirmative

defense of laches, bears the burden of proof. To prevail on

laches, respondent is required to establish that there was

undue or unreasonable delay by petitioner in asserting its

17

Cancellation No. 92032202

rights, and prejudice to respondent resulting from the

delay. Bridgestone/Firestone Research Inc. v. Automobile

Club de l’Ouest de la France, 245 F.3d 1359, 58 USPQ2d 1460

(Fed. Cir. 2001). See also: National Cable Television

Association, Inc. v. American Cinema Editors, Inc., 937 F.2d

1572, 19 USPQ2d 1424 (Fed. Cir. 1991) [laches runs from the

time from which action could be taken against the trademark

rights inhering upon registration].

In the present case, respondent’s mark was published

for opposition on July 5, 1994;6 issuance of respondent’s

registration on the Principal Register occurred on July 16,

1996; and the petition for cancellation was filed on July

13, 2001. Thus, the delay comprises a little over seven

years. Petitioner has been completely silent as to the

reason for its delay, and we consider the unexplained delay

of over seven years to be substantial.

As petitioner points out, however, mere delay in

asserting a trademark-related right does not necessarily

result in changed conditions sufficient to support the

defense of laches. There must also have been some detriment

to the defendant due to the delay. Bridgestone/Firestone

Research Inc. v. Automobile Club de l’Ouest de la France,

supra at 1463. Prejudice is generally shown by the fact

6

Respondent was not aware of petitioner’s registered mark when

it filed the underlying application. (Hoffman dep., p. 183).

18

Cancellation No. 92032202

that in reliance on petitioner’s silence, respondent built

up a valuable business and good will around the mark during

the time petitioner never objected. Turner v. Hops Grill

and Bar Inc., 52 USPQ2d 1310 (TTAB 1999). See generally:

J.T. McCarthy, McCarthy on Trademarks and Unfair

Competition, §20:76 (4th ed. 2004).

Economic prejudice arises when a defendant suffers the

loss of monetary investments or incurs damage that likely

would have been prevented by an earlier suit. A.C. Aukerman

Co. v. R. L. Chaides Construction Co., 960 F.2d 1020, 22

USPQ2d 1321 (Fed. Cir. 1992). A nexus must be shown between

the delay in filing suit and the expenditures; the alleged

infringer must change his position because of and as a

result of the plaintiff’s delay. The essential inquiry is

to determine if there was a change in the economic position

of the alleged infringer during the period of delay. State

Contracting & Engineering Corp. v. Condotte America, Inc.,

346 F.3d 1057, 68 USPQ2d 1481 (Fed. Cir. 2003).

Respondent has provided insufficient specifics about

the detriment it alleges to have suffered. Respondent has

failed to provide any dollar amounts regarding the costs of

development and promotion of its product marketed under the

mark ONCASE. Respondent has shipped only seven vials of

product for testing. In addition to these shipments,

19

Cancellation No. 92032202

according to Dr. Hoffman, respondent has promoted its

product at conferences and trade shows by way of posters and

distribution of informational handouts. More specifically,

respondent promoted its product, in the period July 1994 to

2003, by way of 21 presentations, 12 meetings and 45 trade

shows. According to Dr. Hoffman, he presents papers, hands

out printed material, and engages in discussions with

potential customers and partners at the trade shows. In its

brief (p. 9), respondent highlights its promotional efforts

at two of the most widely attended events, namely the

American Association of Cancer Research annual meeting and

the American Society of Clinical Oncology annual meeting,

drawing 10,000 and 15,000 attendees, respectively. At each

recent meeting, respondent distributed about 200 copies of a

bibliography of articles about the ONCASE brand drug. Dr.

Hoffman further testified that scientific information,

technical bulletins and posters were available at

respondent’s booths. Respondent also has promoted its drug

at other meetings and conferences, giving presentations to

oncologists and/or scientists in the field of cancer

research. Dr. Hoffman testified that the presentations

generally attract 50-100 attendees. Dr. Hoffman also

testified that respondent’s website counted more than 13,000

visits in a recent one-year period.

20

Cancellation No. 92032202

Although respondent contends that its investment in the

ONCASE brand product has been extensive, it is difficult to

gauge, in the absence of dollar amounts or other specific

information relative to its promotional efforts, the degree

to which there has been any detriment. We also lack any

testimony or other evidence which would shed light on the

effect and success of respondent’s promotional efforts.

Further, respondent’s testimony regarding its appearances at

conferences, trade shows and presentations is diminished by

the fact that it was promoting other drugs at the same time.

For example, exhibit no. 11 to Dr. Hoffman’s depostion is a

photograph of one of respondent’s booths at a trade show; no

fewer than four of respondent’s other drugs are being

promoted under different marks. Thus, in all likelihood,

respondent’s expenditures in connection with the promotion

of its ONCASE brand drug would appear to be little more than

what it was spending in any event to promote its other

drugs. That is to say, respondent might very well have

attended the various trade shows and conferences to promote

its other drugs even if its ONCASE brand drug had not been

developed. Again, in the absence of details relating to the

specific economic prejudice suffered, we are unable to say

that respondent has established a meritorious laches

defense.

21

Cancellation No. 92032202

Further, while Dr. Hoffman has authored scientific

papers concerning respondent’s drug, the drug is hardly ever

referred to by its trademark ONCASE; instead, it is called

by its scientific name (recombinant methioninase).

In sum, respondent has failed to put forward sufficient

evidence of material prejudice to support a finding of

laches. Accordingly, we find that respondent’s laches

defense fails for lack of proof.

Decision: The petition for cancellation grounded on

likelihood of confusion is granted. Registration No.

1,987,445 will be cancelled in due course.

22

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