National Heart, Lung, and Blood Institute; Proposed Collection; Comment Request The Multi-Ethnic Study of Atherosclerosis

DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health and Human Services

National Heart, Lung, and Blood Institute; Proposed Collection;

Comment Request The Multi-Ethnic Study of Atherosclerosis

Summary

In compliance with the requirement of Section 3506(c)(2)(A) of the

Paperwork Reduction Act of 1995, for opportunity for public comment on

proposed data collection projects, the National Heart, Lung, and Blood

Institute (NHLBI), the National Institutes of Health (NIH) will publish

periodic summaries of proposed projects to be submitted to the Office

of Management and Budget (OMB) for review and approval.

Proposed Collection

Title: The Multi-Ethnic Study of Atherosclerosis.

Type of Information Request: New.

Need and Use of Information Collection: MESA is a cohort study

evaluating people aged 45-84 years and measures of subclinical disease

cardiovascular disease (disease detected before it has produced signs

and symptoms) that predict progression to clinically overt disease in a

diverse population. The purpose is to develop population-based methods

for identifying asymptomatic people at high risk of clinical events.

The results of this study will allow application for future screening

for identification of people at increased risk for cardiovascular

disease and intervention studies for treatment of those at increased

risk. This study will include a substantial proportion of previously

understudied minority groups.

Need and use of Information Collection; Frequency of Response;

Affected Public and Type of Respondents: The annual reporting burden is

as follows:

Estimated number of Respondents: 16,514;

Estimated Responses/Respondent: 3.88;

Average Burden Hours/Response: 4.55; and

Estimated Total Annual Burden Hours Requested: 25,070.

There are no costs for respondents. Estimated annualized cost for

information collection for information collection for a 10-year period

(in thousands) is $6870. The estimated annualized start-up costs are

$756, and the estimated annualized operating and maintenance costs are

$6114.

Request for Comments

Written comments and/or suggestions from the public and affected

agencies are invited on one or more of the following points: (1)

Whether the proposed collection of information will have practical

utility; (2) The accuracy of the agency's estimate of burden of the

proposed collection of information, including the validity of the

methodology and assumptions used; (3) Ways to enhance the quality,

utility, and clarity of the information to be collected; and (4) Ways

to minimize the burden of collection of information on those who are to

respond, including the use of appropriate automated, electronic,

mechanical, or other technological collection techniques or other forms

of information technology.

For Further Information

To request more information on the proposed project or to obtain a

copy of data collection plans and instruments, contact Dr. Robin

Boineau, Epidemiology and Biometry Program, Division of Epidemiology

and Clinical Applications, NHLBI, NIH, II Rockledge Centre, 6701

Rockledge Drive, MSC # 7934, Bethesda, MD, 20892-7934, or call non-

toll-free number (301) 435-0707, or E-mail your request, including your

address to: [email protected].

[[Page 73564]]

Comments Due Date

Comments regarding this information collection are best assured of

having their full effect if received on or before February 28, 2000.

Dated: December 22, 1999.

Peter Savage,

Acting Director, Division of Epidemiology and Clinical Applications.

[FR Doc. 99-33910 Filed 12-29-99; 8:45 am]

BILLING CODE 4140-01-M