Proposed Data Collections Submitted for Public Comment and Recommendations

DEPARTMENT OF HEALTH AND HUMAN SERVICES

Centers for Disease Control and Prevention

[INFO-98-12]

Proposed Data Collections Submitted for Public Comment and

Recommendations

In compliance with the requirement of section 3506(c)(2)(A) of the

Paperwork Reduction Act of 1995 for opportunity for public comment on

proposed data collection projects, the Centers for Disease Control and

Prevention (CDC) will publish periodic summaries of proposed projects.

To request more information on the proposed projects or to obtain a

copy of the data collection plans and instruments, call the CDC Reports

Clearance Officer on (404) 639-7090.

Comments are invited on: (a) Whether the proposed collection of

information is necessary for the proper performance of the functions of

the agency, including whether the information shall have practical

utility; (b) the accuracy of the agency's estimate of the burden of the

proposed collection of information; (c) ways to enhance the quality,

utility, and clarity of the information to be collected; and (d) ways

to minimize the burden of the collection of information on respondents,

including through the use of automated collection techniques for other

forms of information technology. Send comments to Seleda Perryman,

Assistant CDC Reports Clearance Officer, 1600 Clifton Road, MS-D24,

Atlanta, GA 30333. Written comments should be received within 60 days

of this notice.

Proposed Project

1. An Epidemiologic Study of the Relation Between Maternal and

Paternal Preconception Exposure to Ionizing Radiation and Childhood

Leukemia (0920-0364)--Extension--The National Center for Environmental

Health proposes an extension of a case-control study of the relation

between maternal and paternal preconception exposure to ionizing

radiation and childhood leukemia. The study is designed to determine

whether preconception gonadal doses from ionizing radiation are higher

in the parents of children with leukemia than in parents of healthy

children. This hypothesis is based on previous study findings that,

compared with control groups, children with leukemia were more likely

to have fathers who worked at the Sellafield nuclear facility in Great

Britain and to have received higher doses of ionizing radiation prior

to the conception of the child. Funding for the study is being provided

to the University of Colorado Health Sciences Center by the National

Center for Environmental Health of the Centers for Disease Control and

Prevention.

The study is designed as a multicenter case-control study. Cases

will be children with leukemia and controls will be children without

leukemia selected at random from the same population as the cases. In

addition, the next older sibling will be used in a second control

group. The main exposure of interest, paternal and maternal gonadal

absorbed doses from ionizing radiation during the six-month time period

before conception, will be quantified by taking detailed histories from

the parents about medical, occupational, and environmental exposures

that they had during the time period of interest. Gonadal doses will be

estimated from the documentation of each exposure. By calculating the

doses of ionizing radiation each parent received, we can compute odds

ratios and confidence intervals for paternal and maternal doses

separately and combined. These findings will clarify whether the

previously determined risks can be detected in other populations with

similar exposures. Consistency in the results of this study with those

of a

[[Page 10636]]

similar study in Great Britain would have a major impact on current

medical practice and occupational exposure standards. If this study

does not detect an elevated risk for leukemia, it will be unlikely that

preconception gonadal doses from ionizing radiation that are received

by the general public are related to childhood leukemia. There is no

cost to the respondents.

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No of Avg. burden/

Respondents No. of responses/ response (in Total burden

respondents respondents hrs.) (in hrs.)

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Pediatric Oncologist Introduction of Study to

Parent(s)...................................... 5 123 0.083 51

Request for Patient Information from Other

Physicians..................................... 5 1 0.166 1

Request for Participation....................... 1,968 1 0.1666 328

Exposure Questionnaire.......................... 1,968 1 2.1666 4,264

Re-interview 10%................................ 197 1 2.16 426

Medical Record Requests......................... 219 1 1 219

Occupational Record Requests.................... 50 5 .5 125

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Total....................................... .............. .............. .............. 5,414

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2. Evaluation of the National Domestic Violence Hotline (NDVH)-

NEW--The National Center for Injury Prevention and Control's Division

of Violence Prevention intends to conduct a survey of 150 local

domestic violence abuse agencies who have received referrals from the

National Domestic Violence Hotline--(1.800.799.SAFE). The specific

topic area for this study relates to whether or not the agencies can

handle the amount of referrals they receive from the NDVH.

The purpose of this survey is to determine:

--The ability of the local agencies to handle NDVH referrals

--The appropriateness of the NDVH referrals

--Basic information about the size and programs offered by the local

agencies

Results from this research will be used to enhance government

programs that support local anti-domestic violence organizations. In

addition, this information will also be used by the NDVH to further

enhance their ability to deliver appropriate referrals to the over

140,000 annual callers. The study will be done by telephone. There is

no cost to the respondents.

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Number of Responses per Hours per Total burden

Type of respondent respondents respondent response hours

----------------------------------------------------------------------------------------------------------------

Local Agency.................................... 150 1 .17 25

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Total....................................... .............. .............. .............. 25

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Dated: February 23, 1998.

Kathy Cahill,

Associate Director for Policy Planning and Evaluation, Centers for

Disease Control and Prevention (CDC).

[FR Doc. 98-5516 Filed 3-3-98; 8:45 am]

BILLING CODE 4163-18-P