Availability of Final Toxicological Profiles

DEPARTMENT OF HEALTH AND HUMAN SERVICES

Agency For Toxic Substances and Disease Registry

[ATSDR-138]

Availability of Final Toxicological Profiles

AGENCY: Agency for Toxic Substances and Disease Registry (ATSDR),

Department of Health and Human Services (HHS).

ACTION: Notice of availability.

-----------------------------------------------------------------------

SUMMARY: This notice announces the availability of five final

toxicological profiles, prepared by ATSDR for the Department of

Defense, on unregulated hazardous substances.

FOR FURTHER INFORMATION CONTACT: Ms. Loretta Norman, Division of

Toxicology, Agency for Toxic Substances and Disease Registry, Mailstop

E-29, 1600 Clifton Road, NE., Atlanta, Georgia 30333, telephone (404)

639-6322.

SUPPLEMENTARY INFORMATION: The Superfund Amendments and Reauthorization

Act (SARA) of 1986 (Public Law 99-499) amended the Comprehensive

Environmental Response, Compensation, and Liability Act (CERCLA or

Superfund) of 1980. Section 211 of SARA also amended Title 10 of the

U.S. Code, creating the Defense Environmental Restoration Program.

Section 2704(a) and (b) of Title 10 of the U.S. Code directs the

Secretary of Defense to notify the Secretary of Health and Human

Services (HHS) of not less than 25 of the most commonly found,

unregulated hazardous substances at defense facilities. The Secretary

of HHS shall take necessary steps to ensure the timely preparation of

toxicological profiles of these substances. Each profile includes an

examination, summary and interpretation of available toxicological

information and epidemiological evaluations. This information and these

data are used to ascertain the levels of significant human exposure for

the substance and the associated health effects. The profiles include a

determination of whether adequate information on the health effects of

each substance is available or under development. When adequate

information is not available, ATSDR, in cooperation with the National

Toxicology Program (NTP), is required to assure initiation of research

to determine these health effects.

Notice of the availability of five new draft toxicological profiles

for public review and comment was published in the Federal Register on

November 26, 1996 (61 FR 60105), with notice of a 90-day public comment

period for each profile, starting from the actual release date.

Following the close of each comment period, chemical-specific comments

were addressed, and where appropriate, changes were incorporated into

each profile.

The public comments, the classification of and response to those

comments, and other data submitted in response to the Federal Register

notice bear the docket control number ATSDR-115. This material is

available for public inspection at the Division of Toxicology, Agency

for Toxic Substances and Disease Registry, Building 4, Suite 2400,

Executive Park Drive, Atlanta, Georgia (not a mailing address), between

8 a.m. and 4:30 p.m., Monday through Friday, except legal holidays.

Availability

This notice announces the availability of five final toxicological

profiles for the Department of Defense. The following toxicological

profiles are now available through the U.S. Department of Commerce,

National Technical Information Service (NTIS), 5285 Port Royal Road,

Springfield, Virginia 22161, telephone 1-800-553-6847. There is a

charge for these profiles as determined by NTIS.

----------------------------------------------------------------------------------------------------------------

Toxicological profile NTIS order No. CAS No.

----------------------------------------------------------------------------------------------------------------

1. 2-BUTOXYETHANOL AND 2-BUTOXYETHANOL ACETATE................................ PB99-102527 000111-76-2

000112-07-2

2. DIISOPROPYL METHYLPHOSPHONATE.............................................. PB99-102535 001445-75-6

3. HEXAMETHYLENE DIISOCYANATE................................................. PB99-102543 000822-06-0

4. JET FUEL (JP-5)............................................................ PB99-102550 008008-20-6

JET FUEL (JP-8)........................................................... ................ 070892-10-3

5. METHYLENEDIANILINE......................................................... PB99-102568 000101-77-9

----------------------------------------------------------------------------------------------------------------

[[Page 59568]]

Dated: October 29, 1998.

Donna Garland,

Acting Director, Office of Policy and External Affairs, Agency for

Toxic Substances and Disease Registry.

[FR Doc. 98-29504 Filed 11-3-98; 8:45 am]

BILLING CODE 4163-70-P