Availability of Final Toxicological Profiles

DEPARTMENT OF HEALTH AND HUMAN SERVICES

Agency For Toxic Substances and Disease Registry

[ATSDR-132]

Availability of Final Toxicological Profiles

AGENCY: Agency for Toxic Substances and Disease Registry (ATSDR),

Department of Health and Human Services (HHS).

ACTION: Notice of availability.

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SUMMARY: This notice announces the availability of nine final

toxicological profiles on unregulated hazardous substances prepared by

ATSDR for the Department of Defense.

FOR FURTHER INFORMATION CONTACT: Ms. Loretta Norman, Division of

Toxicology, Agency for Toxic Substances and Disease Registry, Mailstop

E-29, 1600 Clifton Road, NE., Atlanta, Georgia 30333, telephone (404)

639-6322.

SUPPLEMENTARY INFORMATION: The Superfund Amendments and Reauthorization

Act (SARA) of 1986 (Pub. L. 99-499) amended the Comprehensive

Environmental Response, Compensation, and Liability Act of 1980

(Superfund) or CERCLA. Section 211 of SARA also amended Title 10 of the

U.S. Code, creating the Defense Environmental Restoration Program.

Section 2704(a) and (b) of Title 10 of the U.S. Code directs the

Secretary of Defense to notify the Secretary of Health and Human

Services of not less than 25 of the most commonly found, unregulated

hazardous substances at defense facilities. The Secretary of HHS shall

take necessary steps to ensure the timely preparation of toxicological

profiles of these substances. Each profile includes an examination,

summary and interpretation of available toxicological information and

epidemiological evaluations. This information and these data are used

to ascertain the levels of significant human exposure for the substance

and the associated health effects. The profiles include a determination

of whether adequate information on the health effects of each substance

is available or under development. When adequate information is not

available, in cooperation with the National Toxicology Program (NTP),

ATSDR may plan a program of research designed to determine these health

effects.

Notice of the availability of nine new draft toxicological profiles

for public review and comment was published in the Federal Register on

October 18, 1994 (59 FR 52549), with notice of a 90-day public comment

period for each profile, starting from the actual release date.

Following the close of each comment period, chemical-specific comments

were addressed, and where appropriate, changes were incorporated into

each profile.

The public comments, the classification of and response to those

comments, and other data submitted in response to the Federal Register

notice bear the docket control number ATSDR-86. This material is

available for public inspection at the Division of Toxicology, Agency

for Toxic Substances and Disease Registry, Building 4, Suite 2400,

Executive Park Drive, Atlanta, Georgia (not a mailing address), between

8 a.m. and 4:30 p.m., Monday through Friday, except legal holidays.

Availability

This notice announces the availability of nine final toxicological

profiles for the Department of Defense. The following toxicological

profiles are now available through the U.S. Department of Commerce,

National Technical Information Service (NTIS), 5285 Port Royal Road,

Springfield, Virginia 22161, telephone 1-800-553-6847. There is a

charge for these profiles as determined by NTIS.

[[Page 67377]]

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Toxicological profile NTIS order No. CAS No.

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1. Di-N-OCTYLPHTHALATE............ PB98-101033 000117-84-0

2. ETHYLENE GLYCOL/............... PB98-101108 000107-21-1

PROPYLENE GLYCOL................ 000057-55-6

3. HEXACHLOROETHANE............... PB98-101041 000067-72-1

4. HMX............................ PB98-101058 002691-41-0

5. HYDRAULIC FLUIDS............... PB98-101066 VARIOUS

6. HYDRAZINES..................... PB98-101025 000302-01-2

1,1-DIMETHYLHYDRAZINE......... 000057-14-7

1,2-DIMETHYLHYDRAZINE......... 000540-73-8

DIMETHYLHYDRAZINE............. 030260-66-3

7. MINERAL-BASED CRANKCASE OIL.... PB98-101066 008002-05-9

8. TITANIUM TETRACHLORIDE......... PB98-101074 007550-45-0

9. WHITE PHOSPHORUS............... PB98-101082 007723-14-0

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Dated: December 17, 1997.

Georgi Jones,

Director, Office of Policy and External Affairs, Agency for Toxic

Substances and Disease Registry.

[FR Doc. 97-33508 Filed 12-23-97; 8:45 am]

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