Proposed Data Collection Available for Public Comment

DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health

Proposed Data Collection Available for Public Comment

In compliance with the requirement of section 3506(c)(2)(A) of the

Paperwork Reduction Act of 1995 for opportunity for public comment on

proposed data collection projects, the National Institutes of Health

(NIH), National Cancer Institute (NCI) will publish periodic summaries

of proposed projects. To request more information on the proposed

project, call Jeffery P. Struewing, M.D., Senior Research Investigator,

at (301) 496-4375.

Comments are invited on: (1) Whether the proposed collection of

information is necessary for the proper performance of the functions of

the agency, including whether the information shall have practical

utility; (b) the accuracy of the agency's estimate of the burden of the

proposed collection of information; (c) ways to enhance the quality,

utility, and clarity of the information to be collected; and (d) ways

to minimize the burden of the collection of information on respondents,

including through the use of automated collection techniques or other

forms of information technology. Send comments to Jeffery P. Struewing,

M.D. National Cancer Institute, Building EPN, Room 439, 6130 Executive

Blvd MSC 7372, Bethesda, MD 20892-7372. Written comments should be

received by January 2, 1996.

Proposed Project: Familial Cancer and the BRCA1 gene--NEW--This

research study will determine how common a particular alteration in the

BRCA1 gene occurs in Jewish individuals, and what the risk of cancer is

in individuals who carry this alteration. With the assistance of Jewish

community leaders in the Washington, D.C. area, Jewish volunteers will

be recruited for the study. In order to determine how representative

the volunteers are, a random sample will also be obtained from the

Washington area. Jewish individuals and a portion of non-Jewish

individuals will be asked to complete the questionnaire. The

questionnaire will include a brief personal medical history, and a

detailed family history of cancer. Participants will be notified of the

overall study results, which may include recommendations about genetic

testing and the availability of testing programs.

------------------------------------------------------------------------

Number of

responses Average

Number of respondents per burden

individual (hours)

------------------------------------------------------------------------

7700.......................................... 1 .33

------------------------------------------------------------------------

Philip D. Amoruso,

NCI Executive Officer.

[FR Doc. 95-27173 Filed 11-2-95; 8:45 am]

BILLING CODE 4140-01-M