Availability of Final Toxicological Profiles

DEPARTMENT OF HEALTH AND HUMAN SERVICES

Agency For Toxic Substances and Disease Registry

[ATSDR-87]

Availability of Final Toxicological Profiles

AGENCY: Agency for Toxic Substances and Disease Registry (ATSDR),

Public Health Service (PHS), Department of Health and Human Services

(HHS).

ACTION: Notice of availability.

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SUMMARY: This notice announces the availability of 6 final and 9

updated final toxicological profiles of priority hazardous substances

comprising the sixth set prepared by ATSDR.

FOR FURTHER INFORMATION CONTACT: Ms. Kim Fears, Agency for Toxic

Substances and Disease Registry, Division of Toxicology, 1600 Clifton

Road, NE., Mail Stop E-29, Atlanta, Georgia 30333, telephone (404) 639-

6304.

SUPPLEMENTARY INFORMATION: The Superfund Amendments and Reauthorization

Act (SARA) (Pub. L. 99-499) amends the Comprehensive Environmental

Response, Compensation, and Liability Act (CERCLA or Superfund) (42

U.S.C. 9601 et seq.) by establishing certain requirements for the ATSDR

and the Environmental Protection Agency (EPA) with regard to hazardous

substances which are most commonly found at facilities on the CERCLA

National Priorities List (NPL). Among these statutory requirements is a

mandate for the Administrator of ATSDR to prepare toxicological

profiles for each substance included on the priority lists of hazardous

substances. These lists identified the 275 hazardous substances which

both agencies determined pose the most significant potential threat to

human health. The availability of the revised list of the 275 most

hazardous substances was announced in the Federal Register on February

28, 1994 (59 FR 9486). For prior versions of the list of substances,

see Federal Register notices dated April 17, 1987, (52 FR 12866);

October 20, 1988, (53 FR 41280); October 26, 1989, (54 FR 43619);

October 17, 1990, (55 FR 42067); October 17, 1991, (56 FR 52166) and

October 28, 1992, (57 FR 48801).

Notice of the availability of drafts of the sixth set (15) of

toxicological profiles for public review and comment was published in

the Federal Register on October 8, 1992, (57 FR 46393), with notice

that a 90-day public comment period would be provided for each profile,

starting from the actual release date. Following the close of each

comment period, chemical-specific comments were addressed, and where

appropriate, changes were incorporated into each profile. The public

comments, the classification of and response to those comments, and

other data submitted in response to the Federal Register notice bear

the docket control number ATSDR-59. This material is available for

public inspection at the Division of Toxicology, Agency for Toxic

Substances and Disease Registry, Building 4, Suite 2400, Executive Park

Drive, Atlanta, Georgia, between 8 a.m. and 4:30 p.m., Monday through

Friday, except legal holidays.

Availability

This notice announces the availability of 6 final and 9 updated

final toxicological profiles comprising the sixth set. The following

toxicological profiles are now available through the U.S. Department of

Commerce, National Technical Information Service (NTIS), 5285 Port

Royal Road, Springfield, Virginia 22161, telephone 1-800-553-6847.

There is a charge for these profiles as determined by NTIS.

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Toxicological profile NTIS Order No. CAS No.

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Sixth Set:

1. Acetone.............. PB/95/100095.............. 67-64-1

2. Carbon Tetrachloride PB/95/100103.............. 56-23-5

(UPDATE).

3. Chlordane (UPDATE)... PB/95/100111.............. 12789-03-6

4. Chlorodibenzofurans.. PB/95/100129.............. ..............

1,3,7,8- .......................... 57117-35-8

Tetrachlorodiphenyl

ene oxide.

2,3,6,8- .......................... 57117-37-0

Tetrachlorodiphenyl

ene oxide.

2,3,7,8- .......................... 51207-31-9

Tetrachlorodiphenyl

ene oxide.

1,2,3,4,8- .......................... 67517-48-0

Pentachlorodiphenyl

ene oxide.

1,2,3,7,8- .......................... 57117-41-6

Pentachlorodiphenyl

ene oxide.

2,3,4,7,8- .......................... 57117-31-4

Pentachlorodiphenyl

ene oxide.

1,2,3,4,7,8- .......................... 70648-26-9

Hexachlorodiphenyle

ne oxide.

1,2,3,6,7,8- .......................... 57117-44-9

Hexachlorodiphenyle

ne oxide.

1,2,3,7,8,9- .......................... 72918-21-9

Hexachlorodiphenyle

ne oxide.

1,2,4,6,7,9- .......................... 75627-02-0

Hexachlorodiphenyle

ne oxide.

2,3,4,6,7,8- .......................... 60851-34-5

Hexachlorodiphenyle

ne oxide.

1,2,3,4,6,7,8- .......................... 67562-39-4

Heptachlorodiphenyl

ene oxide.

1,2,3,4,6,7,9- .......................... 70648-25-8

Heptachlorodiphenyl

ene oxide.

1,2,3,4,6,8,9- .......................... 69698-58-4

Heptachlorodiphenyl

ene oxide.

1,2,3,4,7,8,9- .......................... 55673-89-7

Heptachlorodiphenyl

ene oxide.

1,2,3,4,6,7,8,9- .......................... 39001-02-0

Octachlorodiphenyle

ne oxide.

5. 4,4'-DDT, DDE, DDD PB/95/100137.............. ..............

(UPDATE).

Dichlorodiphenyltric .......................... 50-29-3

hloroethane (DDT).

Dichlorodiphenyldich .......................... 72-55-9

loroethylene (DDE).

1,1,-bis(4- .......................... 72-54-8

chlorophenyl)-2,2-

dichloroethane

(DDD).

6. 1,2-Dichloroethane PB/95/100145.............. 107-06-2

(UPDATE).

7. 1,1-Dichloroethene PB/95/100152.............. 75-35-4

(UPDATE).

8. Hexachlorobutadiene.. PB/95/100160.............. 87-68-3

9. PB/95/100178.............. ..............

Hexachlorocyclohexanes.

Gamma- .......................... 58-89-9

Hexachlorocyclohexa

ne.

Alpha- .......................... 319-84-6

Hexachlorocyclohexa

ne.

Beta- .......................... 319-85-7

Hexachlorocyclohexa

ne.

Delta- .......................... 319-86-8

Hexachlorocyclohexa

ne.

10. MBOCA............... PB/95/100186.............. 101-14-4

11. Mercury (UPDATE).... PB/95/100194.............. 7439-97-6

12. Methoxychlor........ PB/95/100202.............. 72-43-5

13. Pentachlorophenol PB/95/100210.............. 87-86-5

(UPDATE).

14. Toluene (UPDATE).... PB/95/100228.............. 108-88-3

15. Zinc (UPDATE)....... PB/95/100236.............. 7440-66-6

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Dated: November 7, 1994.

Claire V. Broome,

Deputy Administrator, Agency for Toxic Substances and Disease Registry.

[FR Doc. 94-27964 Filed 11-10-94; 8:45 am]

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