# 21 CFR § 172.379: Vitamin D2

> Federal · Regulations · In force

URL: https://www.frixlaw.com/law-library/statutes/ecfr-21-172.379

## Section

- **Citation:** 21 CFR § 172.379
- **Heading:** Vitamin D2
- **Jurisdiction:** Federal
- **Kind:** Regulations
- **Status:** In force
- **Text as of:** September 22, 2026
- **Source:** Publisher's official text
- **Location:** Title 21—Food and Drugs > CHAPTER I—FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES > SUBCHAPTER B—FOOD FOR HUMAN CONSUMPTION > PART 172—FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION > Subpart D—Special Dietary and Nutritional Additives

## Text

Vitamin D2 may be used safely in foods as a nutrient supplement defined under § 170.3(o)(20) of this chapter in accordance with the following prescribed conditions:
(a) Vitamin D2, also known as ergocalciferol, is the chemical 9,10-seco(5Z,7E,22E)-5,7,10(19),22-ergostatetraen-3-ol. Vitamin D2 is produced by ultraviolet irradiation of ergosterol isolated from yeast and is purified by crystallization.
(b) Vitamin D2 meets the specifications of the 2015 Food Chemical Codex, 9th edition (through Third Supplement), effective December 1, 2015, pp. 1260-1261, which is incorporated by reference. The Director of the Office of the Federal Register approves this incorporation by reference in accordance with 5 U.S.C. 552(a) and 1 CFR part 51. You may obtain copies from the United States Pharmacopeial Convention, 12601 Twinbrook Pkwy., Rockville, MD 20852 (Internet address http://www.usp.org). Copies may be examined at the Dockets Management Staff (HFA-305), Food and Drug Administration, 5630 Fishers Lane, Rm. 1061, Rockville, MD 20852, 240-402-7500, between 9 a.m. and 4 p.m., Monday through Friday, or at the National Archives and Records Administration (NARA). For information on the availability of this material at NARA, call 202-741-6030 or go to: http://www.archives.gov/federal-register/cfr/ibr-locations.html.
(c) The additive may be used as follows:
Category of Food
Maximum Levels in Food (as Served)
Edible plant-based beverages intended as milk alternatives
84 IU/100 g.
Edible plant-based yogurt alternatives
89 IU/100 g.
Soy beverage products
89 IU/100 g
Soy-based butter substitute spreads
330 IU/100 g
Soy-based cheese substitutes and soy-based cheese substitute products
270 IU/100 g
[74 FR 11022, Mar. 16, 2009, as amended at 78 FR 71463, Nov. 29, 2013; 81 FR 46581, July 18, 2016; 88 FR 17719, Mar. 24, 2023]

## Nearby sections

- [21 CFR § 172.5 § 172.5 General provisions for direct food additives.](https://www.frixlaw.com/law-library/statutes/ecfr-21-172.5.md)
- [21 CFR § 172.105 § 172.105 Anoxomer.](https://www.frixlaw.com/law-library/statutes/ecfr-21-172.105.md)
- [21 CFR § 172.110 § 172.110 BHA.](https://www.frixlaw.com/law-library/statutes/ecfr-21-172.110.md)
- [21 CFR § 172.115 § 172.115 BHT.](https://www.frixlaw.com/law-library/statutes/ecfr-21-172.115.md)
- [21 CFR § 172.120 § 172.120 Calcium disodium EDTA.](https://www.frixlaw.com/law-library/statutes/ecfr-21-172.120.md)
- [21 CFR § 172.130 § 172.130 Dehydroacetic acid.](https://www.frixlaw.com/law-library/statutes/ecfr-21-172.130.md)
- [21 CFR § 172.133 § 172.133 Dimethyl dicarbonate.](https://www.frixlaw.com/law-library/statutes/ecfr-21-172.133.md)
- [21 CFR § 172.135 § 172.135 Disodium EDTA.](https://www.frixlaw.com/law-library/statutes/ecfr-21-172.135.md)
- [21 CFR § 172.140 § 172.140 Ethoxyquin.](https://www.frixlaw.com/law-library/statutes/ecfr-21-172.140.md)
- [21 CFR § 172.145 § 172.145 Heptylparaben.](https://www.frixlaw.com/law-library/statutes/ecfr-21-172.145.md)
- [21 CFR § 172.150 § 172.150 4-Hydroxymethyl-2,6-di-tert-butylphenol.](https://www.frixlaw.com/law-library/statutes/ecfr-21-172.150.md)
- [21 CFR § 172.155 § 172.155 Natamycin (pimaricin).](https://www.frixlaw.com/law-library/statutes/ecfr-21-172.155.md)
- [21 CFR § 172.160 § 172.160 Potassium nitrate.](https://www.frixlaw.com/law-library/statutes/ecfr-21-172.160.md)
- [21 CFR § 172.165 § 172.165 Quaternary ammonium chloride combination.](https://www.frixlaw.com/law-library/statutes/ecfr-21-172.165.md)

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Source: Frix Law Library, https://www.frixlaw.com/law-library/statutes/ecfr-21-172.379. Check the current official text before relying on it. Not legal advice.