# 21 CFR § 172.105: Anoxomer

> Federal · Regulations · In force

URL: https://www.frixlaw.com/law-library/statutes/ecfr-21-172.105

## Section

- **Citation:** 21 CFR § 172.105
- **Heading:** Anoxomer
- **Jurisdiction:** Federal
- **Kind:** Regulations
- **Status:** In force
- **Text as of:** September 22, 2026
- **Source:** Publisher's official text
- **Location:** Title 21—Food and Drugs > CHAPTER I—FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES > SUBCHAPTER B—FOOD FOR HUMAN CONSUMPTION > PART 172—FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION > Subpart B—Food Preservatives

## Text

Anoxomer as identified in this section may be safely used in accordance with the following conditions:
(a) Anoxomer is 1,4-benzenediol, 2-(1,1-dimethylethyl)-polymer with diethenylbenzene, 4-(1,1-dimethyl-ethyl)phenol, 4- methoxyphenol, 4,4′-(1-methylethylidene)bis(phenol) and 4-methylphenol (CAS Reg. No. 60837-57-2) prepared by condensation polymerization of divinylbenzene (m- and p-) with tert-butylhydroquinone, tert-butylphenol, hydroxyanisole, p-cresol and 4,4′-isopropylidenediphenol.
(b) The polymeric antioxidant meets the following specifications:
(1) Polymer, not less than 98.0 percent as determined by an ultraviolet method entitled “Ultraviolet Assay, “1982, which is incorporated by reference. Copies are available from the Office of Food Additive Safety (HFS-200), Center for Food Safety and Applied Nutrition, Food and Drug Administration, 5001 Campus Dr., College Park, MD 20740, 240-402-1200, or at the National Archives and Records Administration (NARA). For information on the availability of this material at NARA, call 202-741-6030, or go to: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html.
(2) Molecular weight: Total monomers, dimers and trimers below 500 not more than 1 percent as determined by a method entitled “Low Molecular Weight Anoxomer Analysis,” 1982, which is incorporated by reference. Copies are available from the Office of Food Additive Safety (HFS-200), Center for Food Safety and Applied Nutrition, Food and Drug Administration, 5001 Campus Dr., College Park, MD 20740, 240-402-1200, or at the National Archives and Records Administration (NARA). For information on the availability of this material at NARA, call 202-741-6030, or go to: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html.
(3) Phenol content: Not less than 3.2 milliequivalent/gram and not more than 3.8 milliequivalent/gram as determined by a method entitled “Total Phenols,” 1982, which is incorporated by reference. Copies are available from the Office of Food Additive Safety (HFS-200), Center for Food Safety and Applied Nutrition, Food and Drug Administration, 5001 Campus Dr., College Park, MD 20740, 240-402-1200, or at the National Archives and Records Administration (NARA). For information on the availability of this material at NARA, call 202-741-6030, or go to: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html.
(4) Heavy metals as lead (as Pb), not more than 10 parts per million. Arsenic (as As), not more than 3 parts per million. Mercury (as Hg), not more than 1 part per million.
(c) Anoxomer may be safely used as an antioxidant in food at a level of not more than 5,000 parts per million based on fat and oil content of the food.
[48 FR 18798, Apr. 26, 1983, as amended at 54 FR 24896, June 12, 1989; 88 FR 17719, Mar. 24, 2023]

## Nearby sections

- [21 CFR § 172.5 § 172.5 General provisions for direct food additives.](https://www.frixlaw.com/law-library/statutes/ecfr-21-172.5.md)
- [21 CFR § 172.105 § 172.105 Anoxomer.](https://www.frixlaw.com/law-library/statutes/ecfr-21-172.105.md)
- [21 CFR § 172.110 § 172.110 BHA.](https://www.frixlaw.com/law-library/statutes/ecfr-21-172.110.md)
- [21 CFR § 172.115 § 172.115 BHT.](https://www.frixlaw.com/law-library/statutes/ecfr-21-172.115.md)
- [21 CFR § 172.120 § 172.120 Calcium disodium EDTA.](https://www.frixlaw.com/law-library/statutes/ecfr-21-172.120.md)
- [21 CFR § 172.130 § 172.130 Dehydroacetic acid.](https://www.frixlaw.com/law-library/statutes/ecfr-21-172.130.md)
- [21 CFR § 172.133 § 172.133 Dimethyl dicarbonate.](https://www.frixlaw.com/law-library/statutes/ecfr-21-172.133.md)
- [21 CFR § 172.135 § 172.135 Disodium EDTA.](https://www.frixlaw.com/law-library/statutes/ecfr-21-172.135.md)
- [21 CFR § 172.140 § 172.140 Ethoxyquin.](https://www.frixlaw.com/law-library/statutes/ecfr-21-172.140.md)
- [21 CFR § 172.145 § 172.145 Heptylparaben.](https://www.frixlaw.com/law-library/statutes/ecfr-21-172.145.md)
- [21 CFR § 172.150 § 172.150 4-Hydroxymethyl-2,6-di-tert-butylphenol.](https://www.frixlaw.com/law-library/statutes/ecfr-21-172.150.md)
- [21 CFR § 172.155 § 172.155 Natamycin (pimaricin).](https://www.frixlaw.com/law-library/statutes/ecfr-21-172.155.md)
- [21 CFR § 172.160 § 172.160 Potassium nitrate.](https://www.frixlaw.com/law-library/statutes/ecfr-21-172.160.md)
- [21 CFR § 172.165 § 172.165 Quaternary ammonium chloride combination.](https://www.frixlaw.com/law-library/statutes/ecfr-21-172.165.md)

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Source: Frix Law Library, https://www.frixlaw.com/law-library/statutes/ecfr-21-172.105. Check the current official text before relying on it. Not legal advice.