# 25 Tex. Admin. Code § 229.427: 25 TAC § 229.427. Licensure Fees > Texas · Regulations · In force URL: https://www.frixlaw.com/law-library/statutes/STATE_TX_TAC_T25_P1_C229_S229_427 ## Section - **Citation:** 25 Tex. Admin. Code § 229.427 - **Heading:** 25 TAC § 229.427. Licensure Fees - **Jurisdiction:** Texas - **Kind:** Regulations - **Status:** In force - **Text as of:** August 14, 2026 - **Source:** Compiled text - **Location:** Texas Administrative Code / Title 25 HEALTH SERVICES / Part 1 DEPARTMENT OF STATE HEALTH SERVICES / Chapter 229 FOOD AND DRUG / 25 TAC § 229.427 ## Text (a) License fee. Except as provided by §229.423 of this subchapter (relating to Exemptions), no person may operate or conduct business as a wholesale distributor of prescription drugs without first obtaining a license from the department. All applicants for an initial wholesale distributor of prescription drugs license or a renewal license must pay a licensing fee unless otherwise exempt as provided by subsection (c) of this section. All fees are nonrefundable. Licenses are issued for two-year terms. A license shall only be issued when all past due license fees and delinquency fees are paid. (1) In-state and out-of-state wholesale distributors of prescription drugs who are not manufacturers must pay a two-year license fee based on the gross annual sales of all drugs. (A) For a wholesale distributor of only medical gases, the fees are: (i) $675 for a two-year license; (ii) $675 for a two-year license issued to a change of ownership; and (iii) $337 for a license amended during the current licensure period due to minor changes. (B) For a wholesale distributor with gross annual drug sales of $0 - $199,999.99, the fees are: (i) $1,080 for a two-year license; (ii) $1,080 for a two-year license issued due to a change of ownership; and (iii) $540 for a license amended during the current licensure period due to minor changes. (C) For a wholesale distributor with gross annual drug sales of $200,000 - $19,999,999.99, the fees are: (i) $1,755 for a two-year license; (ii) $1,755 for a two-year license issued due to a change of ownership; and (iii) $877 for a license amended during the current licensure period due to minor changes. (D) For a wholesale distributor with gross annual drug sales greater than or equal to $20 million, the fees are: (i) $2,295 for a two-year license; (ii) $2,295 for a two-year license issued due to a change of ownership; and (iii) $1,147 for a license amended during the current licensure period due to minor changes. (2) In-state and out-of-state wholesale distributors of medical gases who are not manufacturers and who also are required to be licensed as a device distributor under §229.439(a) of this chapter (relating to Licensure Fees) or as a wholesale food distributor under §229.182(a)(3) of this chapter (relating to Licensing/Registration Fee and Procedures) must pay a combined two-year license fee for each place of business. License fees are based on the combined gross annual sales of these regulated products (medical gases, foods, drugs, and devices) as follows: (A) For combined gross annual sales of $0 - $199,999.99, the fees are: (i) $540 for a two-year license; (ii) $540 for a two-year license issued due to a change of ownership; and (iii) $270 for a license amended during the current licensure period due to minor changes. (B) For combined gross annual sales of $200,000 - $499,999.99, the fees are: (i) $810 for a two-year license; (ii) $810 for a two-year license issued due to a change of ownership; and (iii) $405 for a license amended during the current licensure period due to minor changes. (C) For combined gross annual sales of $500,000 - $999,999.99, the fees are: (i) $1,080 for a two-year license; (ii) $1,080 for a two-year license issued due to a change of ownership; and (iii) $540 for a license amended during the current licensure period due to minor changes. (D) For combined gross annual sales of $1 million - $9,999,999.99, the fees are: (i) $1,350 for a two-year license; (ii) $1,350 for a two-year license issued due to a change of ownership; and (iii) $675 for a license issued during the current licensure period due to minor changes. (E) For combined gross annual sales greater than or equal to $10 million, the fees are: (i) $2,025 for a two-year license; (ii) $2,025 for a two-year license issued due to a change of ownership; and (iii) $1,012 for a license amended during the current licensure period due to minor changes. (3) In-state and out-of-state manufacturers of only medical gases must pay a two-year license fee based on the gross annual sales of all prescription drugs as follows. (A) For gross annual drug sales of $0 - $199,999.99, the fees are: (i) $1,080 for a two-year license; (ii) $1,080 for a two-year license issued due to a change of ownership; and (iii) $540 for a license amended during the current licensure period due to minor changes. (B) For gross annual drug sales of $200,000 - $19,999,999.99, the fees are: (i) $1,755 for a two-year license; (ii) $1,755 for a two-year license issued due to a change of ownership; and (iii) $877 for a license amended during the current licensure period due to minor changes. (C) For gross annual drug sales greater than or equal to $20 million, the fees are: (i) $2,295 for a two-year license; (ii) $2,295 for a two-year license issued due to a change of ownership; and (iii) $1,147 for a license amended during the current licensure period due to minor changes. (4) In-state and out-of-state manufacturers of prescription drugs must pay a two-year license fee based on the gross annual sales of all drugs as follows. (A) For gross annual drug sales of $0 - $199,999.99, the fees are: (i) $1,080 for a two-year license; (ii) $1,080 for a two-year license issued due to a change of ownership; and (iii) $540 for a license amended during the current licensure period due to minor changes. (B) For gross annual drug sales of $200,000 - $1,999,999.99, the fees are: (i) $1,350 for a two-year license; (ii) $1,350 for a two-year license issued due to a change of ownership; and (iii) $697 for a license amended during the current licensure period due to minor changes. (C) For gross annual drug sales of $2 million - $9,999,999.99, the fees are: (i) $1,620 for a two-year license; (ii) $1,620 for a two-year license issued due to a change of ownership; and (iii) $847 for a license amended during the current licensure period due to minor changes. (D) For gross annual drug sales of $10 million to $19,999,999.99, the fees are: (i) $1,890 for a two-year license; (ii) $1,890 for a two-year license issued due to a change of ownership; and (iii) $997 for a license amended during the current licensure period due to minor changes. (E) For gross annual drug sales greater than or equal to $20 million, the fees are: (i) $2,295 for a two-year license; (ii) $2,295 for a two-year license issued due to a change of ownership; and (iii) $1,147 for a license amended during the current licensure period due to minor changes. (b) Replacement license fee. The replacement license fee is $100. (c) Proration of license fees. A person having more than one place of business may request a one-time proration of the license fees when applying for a license for each new place of business. Upon approval by the department, the license for the new place of business will have a renewal date the same as the firm's other licensed places of business. (d) Exemption from license fees. A person is exempt from the license fees required by this section if the person is a charitable organization, as described in the Internal Revenue Code of 1986, 26 USC §501 (c)(3), or a nonprofit affiliate of the organization, to the extent otherwise permitted by law. ## Nearby sections - [25 Tex. Admin. Code § 229.419 25 TAC § 229.419. Purpose](https://www.frixlaw.com/law-library/statutes/STATE_TX_TAC_T25_P1_C229_S229_419.md) - [25 Tex. Admin. Code § 229.420 25 TAC § 229.420. Applicable Laws and Regulations](https://www.frixlaw.com/law-library/statutes/STATE_TX_TAC_T25_P1_C229_S229_420.md) - [25 Tex. Admin. Code § 229.421 25 TAC § 229.421. Definitions](https://www.frixlaw.com/law-library/statutes/STATE_TX_TAC_T25_P1_C229_S229_421.md) - [25 Tex. Admin. Code § 229.422 25 TAC § 229.422. Sale of a Prescription Drug](https://www.frixlaw.com/law-library/statutes/STATE_TX_TAC_T25_P1_C229_S229_422.md) - [25 Tex. Admin. Code § 229.423 25 TAC § 229.423. Exemptions](https://www.frixlaw.com/law-library/statutes/STATE_TX_TAC_T25_P1_C229_S229_423.md) - [25 Tex. Admin. Code § 229.424 25 TAC § 229.424. Licensure Requirements](https://www.frixlaw.com/law-library/statutes/STATE_TX_TAC_T25_P1_C229_S229_424.md) - [25 Tex. Admin. Code § 229.425 25 TAC § 229.425. Licensing Procedures](https://www.frixlaw.com/law-library/statutes/STATE_TX_TAC_T25_P1_C229_S229_425.md) - [25 Tex. Admin. Code § 229.426 25 TAC § 229.426. Report of Changes](https://www.frixlaw.com/law-library/statutes/STATE_TX_TAC_T25_P1_C229_S229_426.md) - [25 Tex. Admin. Code § 229.427 25 TAC § 229.427. Licensure Fees](https://www.frixlaw.com/law-library/statutes/STATE_TX_TAC_T25_P1_C229_S229_427.md) - [25 Tex. Admin. Code § 229.428 25 TAC § 229.428. Refusal, Cancellation, Suspension or Revocation of License](https://www.frixlaw.com/law-library/statutes/STATE_TX_TAC_T25_P1_C229_S229_428.md) - [25 Tex. Admin. Code § 229.429 25 TAC § 229.429. Minimum Standards for Licensure](https://www.frixlaw.com/law-library/statutes/STATE_TX_TAC_T25_P1_C229_S229_429.md) - [25 Tex. Admin. Code § 229.430 25 TAC § 229.430. Enforcement and Penalties](https://www.frixlaw.com/law-library/statutes/STATE_TX_TAC_T25_P1_C229_S229_430.md) --- Source: Frix Law Library, https://www.frixlaw.com/law-library/statutes/STATE_TX_TAC_T25_P1_C229_S229_427. Check the current official text before relying on it. Not legal advice.