# MPEP § 2164.01(b): How to Make the Claimed Invention

> Federal · Agency guidance · In force

URL: https://www.frixlaw.com/law-library/statutes/MPEP_S2164.01(b)

## Section

- **Citation:** MPEP § 2164.01(b)
- **Heading:** How to Make the Claimed Invention
- **Jurisdiction:** Federal
- **Kind:** Agency guidance
- **Status:** In force
- **Text as of:** August 14, 2026
- **Source:** Compiled text
- **Location:** USPTO MPEP / Chapter 2100 - Patentability / MPEP § 2164.01(b)

## Text

As long as the specification discloses at least one method for
making and using the claimed invention that bears a reasonable correlation to the
entire scope of the claim, then the enablement requirement of
35 U.S.C. 112
is satisfied.
In re Fisher,
427 F.2d 833, 839, 166 USPQ 18, 24
(CCPA 1970). Failure to disclose other methods by which the claimed invention may be
made does not render a claim invalid under
35 U.S.C. 112
.
Spectra-Physics, Inc. v. Coherent, Inc
., 827 F.2d 1524, 1533, 3
USPQ2d 1737, 1743 (Fed. Cir. 1987),
cert. denied,
484 U.S. 954
(1987).
Naturally, for unstable and transitory chemical intermediates, the
“how to make” requirement does not require that the applicant teach how to make the
claimed product in stable, permanent or isolatable form.
In re
Breslow,
616 F.2d 516, 521, 205 USPQ 221, 226 (CCPA 1980).
A key issue that can arise when determining whether the
specification is enabling is whether the starting materials or apparatus necessary to
make the invention are available. In the biotechnical area, this is often true when
the product or process requires a particular strain of microorganism and when the
microorganism is available only after extensive screening.
The court in
In re Ghiron,
442 F.2d 985, 991, 169
USPQ 723, 727 (CCPA 1971), made clear that if the practice of a method requires a
particular apparatus, the application must provide a sufficient disclosure of the
apparatus if the apparatus is not readily available. The same can be said if certain
chemicals are required to make a compound or practice a chemical process.
In
re Howarth,
654 F.2d 103, 105, 210 USPQ 689, 691 (CCPA 1981).

## Nearby sections

- [MPEP § 2103 Patent Examination Process](https://www.frixlaw.com/law-library/statutes/MPEP_S2103.md)
- [MPEP § 2104 Requirements of 35 U.S.C. 101](https://www.frixlaw.com/law-library/statutes/MPEP_S2104.md)
- [MPEP § 2104.01 Barred by Atomic Energy Act](https://www.frixlaw.com/law-library/statutes/MPEP_S2104.01.md)
- [MPEP § 2105 Patent Eligible Subject Matter — Living Subject Matter](https://www.frixlaw.com/law-library/statutes/MPEP_S2105.md)
- [MPEP § 2106 Patent Subject Matter Eligibility](https://www.frixlaw.com/law-library/statutes/MPEP_S2106.md)
- [MPEP § 2106.01 [Reserved]](https://www.frixlaw.com/law-library/statutes/MPEP_S2106.01.md)
- [MPEP § 2106.02 [Reserved]](https://www.frixlaw.com/law-library/statutes/MPEP_S2106.02.md)
- [MPEP § 2106.03 Eligibility Step 1: The Four Categories of Statutory Subject Matter](https://www.frixlaw.com/law-library/statutes/MPEP_S2106.03.md)
- [MPEP § 2106.04 Eligibility Step 2A: Whether a Claim is Directed to a Judicial Exception](https://www.frixlaw.com/law-library/statutes/MPEP_S2106.04.md)
- [MPEP § 2106.04(a) Abstract Ideas](https://www.frixlaw.com/law-library/statutes/MPEP_S2106.04(a).md)
- [MPEP § 2106.04(a)(1) Examples of Claims That Do Not Recite Abstract Ideas](https://www.frixlaw.com/law-library/statutes/MPEP_S2106.04(a)(1).md)
- [MPEP § 2106.04(a)(2) Abstract Idea Groupings](https://www.frixlaw.com/law-library/statutes/MPEP_S2106.04(a)(2).md)
- [MPEP § 2106.04(a)(3) Tentative Abstract Ideas](https://www.frixlaw.com/law-library/statutes/MPEP_S2106.04(a)(3).md)
- [MPEP § 2106.04(b) Laws of Nature, Natural Phenomena & Products of Nature](https://www.frixlaw.com/law-library/statutes/MPEP_S2106.04(b).md)

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Source: Frix Law Library, https://www.frixlaw.com/law-library/statutes/MPEP_S2164.01(b). Check the current official text before relying on it. Not legal advice.